What is the catalog number for RBM25 Antibody - middle region (ARP74780_P050)?

The catalog number for RBM25 Antibody - middle region (ARP74780_P050) is ARP74780_P050.

What sizes are available for RBM25 Antibody - middle region (ARP74780_P050)?

RBM25 Antibody - middle region (ARP74780_P050) is available in the following size(s): 100 µL.

Is RBM25 Antibody - middle region (ARP74780_P050) in stock?

RBM25 Antibody - middle region (ARP74780_P050) is currently made to order / not held in immediate stock. Contact us for lead time.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

RBM25 Antibody - middle region (ARP74780_P050)

Selected Variant

ARP74780_P050

Size: 100 µL

Product Specifications

CAS Number

9007-83-4

Gene Name

RNA binding motif protein 25

Gene Aliases

S164, NET52, RNPC7, Snu71, RED120, fSAP94

Gene ID

58517

Swiss Prot

P49756

Accession Number

NP_067062.1

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human RBM25

Target

RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5'-splice site (5'-ss) selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5'-ss usage through the 5'-CGGGCA-3' RNA sequence. Its association with LUC7L3 promotes U1 snRNP binding to a weak 5' ss in a 5'-CGGGCA-3'-dependent manner. Binds to the exonic splicing enhancer 5'-CGGGCA-3' RNA sequence located within exon 2 of the BCL2L1 pre-mRNA. Also involved in the generation of an abnormal and truncated splice form of SCN5A in heart failure.

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

DRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERER

Applications

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

92 kDa

Protein Length

843

NCBI Gene Symbol

RBM25

Host or Source

Rabbit

Protein Name

RNA-binding protein 25

Gene Name URL

RBM25

Nucleotide Accession Number

NM_021239.2

Price

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