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NDUFS8 Antibody - C-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

NADH:ubiquinone oxidoreductase core subunit S8

Gene Aliases

TYKY, CI-23k, CI23KD, MC1DN2

Gene ID

4728

Swiss Prot

O00217

Accession Number

XP_005274071

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human NDUS8

Target

This gene encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome.

Partner Proteins

MDM2; vpr; SURF1; SDHA; RPLP0; RAB5B; PSEN1; OPA1; NDUFV2; NDUFS6; NDUFV1; NDUFS3; NDUFS2; NDUFS1; MPV17; HSPA9; DHODH; CYC1; COX15; ABCC2; NDUFS7; RHOT2; NDUFAF3; SAMM50; UBC; GEM; ICT1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

EPRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEE

Applications

WB

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

23kDa

Protein Length

210

NCBI Gene Symbol

NDUFS8

Host or Source

Rabbit

Protein Name

NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial

Gene Name URL

NDUFS8

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