MBNL2 Antibody - N-terminal region
Product Specifications
CAS Number
9007-83-4
Gene Name
Muscleblind like splicing regulator 2
Gene Aliases
MBLL, MBLL39, PRO2032
Gene ID
10150
Swiss Prot
Q5VZF2-2
Accession Number
NP_001292999.1
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human MBNL2
Target
This gene is a member of the muscleblind protein family which was initially described in Drosophila melanogaster. This gene encodes a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined.
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
CRQFQRGTCSRSDEECKFAHPPKSCQVENGRVIACFDSLKGRCSRENCKY
Applications
WB
Purification
Affinity purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
40 kDa
Protein Length
367
NCBI Gene Symbol
MBNL2
Host or Source
Rabbit
Protein Name
Muscleblind-like protein 2
Gene Name URL
MBNL2
Nucleotide Accession Number
NM_001306070.1
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