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MBNL2 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Muscleblind like splicing regulator 2

Gene Aliases

MBLL, MBLL39, PRO2032

Gene ID

10150

Swiss Prot

Q5VZF2-2

Accession Number

NP_001292999.1

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human MBNL2

Target

This gene is a member of the muscleblind protein family which was initially described in Drosophila melanogaster. This gene encodes a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined.

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

CRQFQRGTCSRSDEECKFAHPPKSCQVENGRVIACFDSLKGRCSRENCKY

Applications

WB

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

40 kDa

Protein Length

367

NCBI Gene Symbol

MBNL2

Host or Source

Rabbit

Protein Name

Muscleblind-like protein 2

Gene Name URL

MBNL2

Nucleotide Accession Number

NM_001306070.1

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