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HDAC4 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Histone deacetylase 4

Gene Aliases

HD4, AHO3, BDMR, HDACA, HA6116, HDAC-4, HDAC-A

Gene ID

9759

Swiss Prot

P56524

Accession Number

NP_006028.2

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human HDAC4

Target

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

SSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDL

Applications

WB

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

119 kDa

Protein Length

1084

NCBI Gene Symbol

HDAC4

Host or Source

Rabbit

Protein Name

Histone deacetylase 4

Gene Name URL

HDAC4

Nucleotide Accession Number

NM_006037.3

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