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SMURF1 Antibody - N-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

SMAD specific E3 ubiquitin protein ligase 1

Gene Aliases

KIAA1625

Gene ID

57154

Swiss Prot

Q9HCE7

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human SMUF1

Target

This gene encodes a ubiquitin ligase that is specific for receptor-regulated SMAD proteins in the bone morphogenetic protein (BMP) pathway. This protein plays a key roll in the regulation of cell motility, cell signalling, and cell polarity. Alternative splicing results in multiple transcript variants encoding different isoforms.

Partner Proteins

UBE2L3; SMURF1; TRIB2; POLR2A; SMAD1; UBC; PTCH1; UBE2M; UBE2D3; NEDD8; SENP8; SMAD7; SMAD4; TRAF4; AXIN1; HCVgp1; EFNB1; FBXL15; FBXO42; RNF11; FBXL5; FBXO21; YWHAQ; SMAD5; SMAD3; SMAD2; BTRC; CCDC88C; HNRNPA3; TUBB; E2F7; CMBL; TIMM50; RBM17; RIOK1; WDR

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

QRLQAQRLRNPDVRGSLQTPQNRPHGHQSPELPEGYEQRTTVQGQVYFLH

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

83kDa

Protein Length

757

NCBI Gene Symbol

SMURF1

Host or Source

Rabbit

Protein Name

E3 ubiquitin-protein ligase SMURF1

Gene Name URL

SMURF1

Frequently Asked Questions

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