SC61B Antibody - N-terminal region (ARP74207_P050)
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Product Specifications
CAS Number
9007-83-4
Gene Name
Sec61 translocon beta subunit
Gene ID
10952
Swiss Prot
P60468
Accession Number
NP_006799
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human SC61B
Target
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript.
Partner Proteins
LOC100355886; ASNA1; BAG6; HSPA8; DNAJB1; HSPA4; ERLIN2; SGTA; EGFR; UBC; OST4; AMFR; ITGA4; FN1; ESR1; SEC61B; EDEM1; AGER; ATP13A2; SPC25; SEC61A1; BCAP31; GET4; UBL4A; SERP1; ARL6; SEC63; TRAM1; APOB; VCAM1
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
PTPSGTNVGSSGRSPSKAVAARAAGSTVRQRKNASCGTRSAGRTTSAGTG
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
10kDa
Protein Length
96
NCBI Gene Symbol
SEC61B
Host or Source
Rabbit
Protein Name
Protein transport protein Sec61 subunit beta
Gene Name URL
SEC61B
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