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RRAGA Antibody - C-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Aliases

FIP1, RAGA, FIP-1

Gene ID

10670

Swiss Prot

Q7L523

Accession Number

NP_006561

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human RRAGA

Target

RRAGA is a guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. It may play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. Also it may alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death.

Partner Proteins

RRAGC; RPTOR; STAU1; UBC; IL7R; ASAP1; CPSF2; CPSF3; CPSF1; CSTF2T; PAPOLA; CPSF4; CSTF3; CDC73; LAMTOR1; NOL8; RRAGA; RRAGD

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

CKEQRDVHRFEKISNIIKQFKLSCSKLAASFQSMEVRNSNFAAFIDIFTS

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

34kDa

Protein Length

313

NCBI Gene Symbol

RRAGA

Host or Source

Rabbit

Gene Name URL

RRAGA

Frequently Asked Questions

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