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PMS1 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

PMS1 homolog 1, mismatch repair system component

Gene Aliases

MLH2, PMSL1, hPMS1, HNPCC3

Gene ID

5378

Swiss Prot

P54277

Accession Number

NP_000525.1

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PMS1

Target

This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.

Partner Proteins

UBC; MSH6; MSH2; MLH1; FAN1; USP5; TOP1; SBF1; RFC4; RFC2; RFC1; REV3L; RANGAP1; PSMC1; PPP2R1A; PMS1; PIK3C2A; PGK1; NONO; MOV10; MCM6; IPO5; KPNA2; CYLD; CDK9; CDC5L; CCNT1; BRCA2; ATR; HELB; PSD2; BRIP1; SBF2; MMS19; RNF123; RNF20; IPO9; UBR5; AKAP9; R

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

PFQNDMHNDESGKNTDDCLNHQISIGDFGYGHCSSEISNIDKNTKNAFQD

Applications

WB

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

102 kDa

Protein Length

932

NCBI Gene Symbol

PMS1

Host or Source

Rabbit

Protein Name

PMS1 protein homolog 1

Gene Name URL

PMS1

Nucleotide Accession Number

NM_000534.4

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