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ARHGAP26 Antibody - middle region

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Product Specifications

CAS Number

9007-83-4

Gene Name

Rho GTPase activating protein 26

Gene Aliases

GRAF, GRAF1, OPHN1L, OPHN1L1

Gene ID

23092

Swiss Prot

Q9UNA1

Accession Number

NP_055886

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of Human RHG26

Target

Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML) . Multiple transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

CDC42EP2; SRPK1; UBC; PTEN; PKN3; PKN1; PTK2; INSR; CDC42; RHOA

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

LWMEAMDGREPVYNSNKDSQSEGTAQLDSIGFSIIRKCIHAVETRGINEQ

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

89kDa

Protein Length

814

NCBI Gene Symbol

ARHGAP26

Host or Source

Rabbit

Protein Name

Rho GTPase-activating protein 26

Gene Name URL

ARHGAP26

Frequently Asked Questions

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