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CIRBP Antibody - middle region

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Product Specifications

CAS Number

9007-83-4

Gene Aliases

CIRP

Gene ID

1153

Swiss Prot

Q14011

Accession Number

NP_001271

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of Human CIRBP

Target

CIRBP is a cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. It acts as a translational activator. Seems to play an essential role in cold- induced suppression of cell proliferation. It binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. It acts as a translational repressor (By similarity) . Promotes assembly of stress granules (SGs), when overexpressed.

Partner Proteins

KHDRBS2; RBMY1F; LNX1; SNRPA; RBMY1A1; HNRNPK; RBMX; MDM2; LOC100132057; RNF2; BMI1; PARK2; SRF; IL7R; FN1; CSNK2A1; HNRNPA0; KHDRBS1; BAG5; SMURF1; PAXIP1; BARD1; RTN4; LSM14A; POLR1C; KHSRP; SF1; TPR; TMPO; PRKAR2A; NUP88; CNOT3; CAPRIN1; HNRNPH2; GTF2F

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

SVDGRQIRVDQAGKSSDNRSRGYRGGSAGGRGFFRGGRGRGRGFSRGGGD

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

18kDa

Protein Length

172

NCBI Gene Symbol

CIRBP

Host or Source

Rabbit

Gene Name URL

CIRBP

Frequently Asked Questions

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