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BMPR1A Antibody - N-terminal region (ARP73773_P050)

Selected Variant

ARP73773_P050

Size: 100 µL

Product Specifications

CAS Number

9007-83-4

Gene Aliases

ALK3, SKR5, CD292, ACVRLK3, 10q23del

Gene ID

657

Swiss Prot

P36894

Accession Number

XP_005270121

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human BMPR1A

Target

The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.

Partner Proteins

UBC; USP15; BMPR1A; ACVR1; PEG10; CAV1; HSP90AA1; BAMBI; SMAD7; SMAD6; SMAD1; MYC; SMURF1; Nedd4; NEDD4L; FST; IGSF1; TSC22D1; RUNX2; SF3B4; GDF6; ZMYND11; TGFBRAP1; BMPR1B; TAB1; GDF9; GDF5; BMPR2; HOXC8; BMP7; BMP6; BMP5; BMP4; BMP2; FKBP1A; FKBP1B

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

GMKSDSDQKKSENGVTLAPEDTLPFLKCYCSGHCPDDAINNTCITNGHCF

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

58kDa

Protein Length

532

NCBI Gene Symbol

BMPR1A

Host or Source

Rabbit

Gene Name URL

BMPR1A

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