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PLCG2 Antibody - middle region (ARP72780_P050)

Product Specifications

CAS Number

9007-83-4

Gene Aliases

FCAS3, APLAID, PLC-IV, PLC-gamma-2

Gene ID

5336

Swiss Prot

P16885

Accession Number

NP_002652

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of Human PLCG2

Target

The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane.

Partner Proteins

UBC; ZNF512B; ERBB2; EGFR; PRKCA; PLD1; IRS1; BLNK; LAT2; LIME1; GAB2; DAPP1; PRKD1; CBLB; GAB1; KHDRBS1; LAT; SH3BP2; LCP2; TEC; SHC1; PLCG2; SYK; BTK; KDR; BLK; ITK; LYN; FLT1; NPM1; LCK; JAK2; JAK1; FCER1G; HCK; FYN; EPOR; CD19; PLXNB1; VAV1; PTPN11

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

ETHLRCAEFELRLTDPVPNPNPHESKPWYYDSLSRGEAEDMLMRIPRDGA

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 92%; Human: 100%; Mouse: 100%; Rabbit: 92%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

139kDa

Protein Length

1265

NCBI Gene Symbol

PLCG2

Host or Source

Rabbit

Gene Name URL

PLCG2

Nucleotide Accession Number

NM_002661

Frequently Asked Questions

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