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XRCC1 Antibody - C-terminal region (ARP72538_P050)

Selected Variant

ARP72538_P050

Size: 100 µL

Product Specifications

CAS Number

9007-83-4

Gene Aliases

RCC, SCAR26

Gene ID

7515

Swiss Prot

P18887

Accession Number

NP_006288

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human XRCC1

Target

The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Partner Proteins

UBC; RPA3; RPA2; RPA1; EED; PNKP; APTX; POLB; CSNK2A1; S100A16; SEPT11; UBAP2L; SEC22B; TIMELESS; MRPL12; RBM4; PPT1; CAND1; SUMO1; Cebpb; POLI; XPO1; SUMO2; PARP1; RNF146; ARL6IP5; POLK; POLD1; PCNA; LIG3; RAN; NCAPG; CHD1L; NEIL1; APLF; PARP2; OGG1; CSN

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

GDTEDELRRVAEQKEHRLPPGQEENGEDPYAGSTDENTDSEEHQEPPDLP

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

70kDa

Protein Length

633

NCBI Gene Symbol

XRCC1

Host or Source

Rabbit

Gene Name URL

XRCC1

Nucleotide Accession Number

NM_006297

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