CAVIN1 Antibody - C-terminal region
Product Specifications
CAS Number
9007-83-4
Gene Name
Caveolae associated protein 1
Gene Aliases
CGL4, PTRF, CAVIN, FKSG13, cavin-1
Gene ID
284119
Swiss Prot
Q6NZI2
Accession Number
NP_036364
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human PTRF
Target
This gene encodes a protein that enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts. This protein regulates rRNA transcription by promoting the dissociation of transcription complexes and the reinitiation of polymerase I on nascent rRNA transcripts. This protein also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins. This protein translocates from caveolae to the cytoplasm after insulin stimulation. Caveolae contain truncated forms of this protein and may be the site of phosphorylation-dependent proteolysis. This protein is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrophy.
Partner Proteins
UBC; SUMO1; EGFR; BAG3; NPM1; MYC; LIPE; DMD; FAM162A; TMED10; NOP56; MYBBP1A; GTF3C4; NOLC1; RPS4X; NHP2L1; ILF3; ILF2; HNRNPH1; FLOT2; DHX9; CAV1; TRIM72; ELAVL1; Incenp; ZNF148; TTF1; NKX2-1; TFF1
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
EESRAERIKRSGLRRVDDFKKAFSKEKMEKTKVRTRENLEKTRLKTKENL
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
42kDa
Protein Length
390
NCBI Gene Symbol
CAVIN1
Host or Source
Rabbit
Protein Name
Caveolae-associated protein 1
Gene Name URL
CAVIN1
Frequently Asked Questions
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