HIST1H4A Antibody - N-terminal region (ARP70540_P050)

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Product Specifications

CAS Number

9007-83-4

Gene Aliases

H4C2, H4C3, H4C4, H4C5, H4C6, H4C8, H4C9, H4FA, H4-16, H4C11, H4C12, H4C13, H4C14, H4C15, HIST1H4A

Gene ID

8359

Swiss Prot

P62805

Accession Number

NP_778224

Reactivity

Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human HIST1H4A

Target

HIST1H4A is a core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Partner Proteins

UBC; DTX3L; RBBP4; H3F3A; CENPA; HIST1H3A; HDAC2; ASB9; ASB16; L3MBTL2; rev; ARFIP1; JMJD6; XPO7; FAF1; HSPH1; SEC23A; PRMT3; RBX1; HIRIP3; CUL1; ZYX; SF1; TTC1; TROVE2; SHMT1; RPL24; PPM1G; OSBP; GFPT1; GARS; CARS; FBXO6; PAN2; PRMT8; RL1; HCVgp1; ITGA4

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

LGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLK

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol