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Eps15l1 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Epidermal growth factor receptor pathway substrate 15-like 1

Gene Aliases

Eps, Eps1, Eps15R, AI593686, Eps15-rs, 9830147J04Rik

Gene ID

13859

Swiss Prot

Q60902

Accession Number

NP_031970

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Eps15l1

Target

Eps15l1 seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. It is involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR) ; internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2.

Partner Proteins

Eed; Cycs; ITSN1; CDC40; EPN2; NUMBL; NUMB; AGFG2; AGFG1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

PFGGDPFKESDPFHSSSSDDFFKKQTKNDPFTSDPFTKNPSLPSKLDPFE

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

100kDa

Protein Length

907

NCBI Gene Symbol

EPS15L1

Host or Source

Rabbit

Protein Name

Epidermal growth factor receptor substrate 15-like 1

Gene Name URL

Eps15l1

Nucleotide Accession Number

NM_007944

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