PARPBP Antibody - C-terminal region
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Product Specifications
CAS Number
9007-83-4
Gene Name
PARP1 binding protein
Gene Aliases
AROM, PARI, C12orf48
Gene ID
55010
Swiss Prot
Q9NWS1-5
Reactivity
Human, Rat, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human PARPBP
Target
PARPBP is required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability. PARPBP antagonizes homologous recombination by interfering with the formation of the RAD51-DNA homologous recombination structure. It binds single-strand DNA and poly (A) homopolymers and positively regulate the poly (ADP-ribosyl) ation activity of PARP1; however such function may be indirect.
Partner Proteins
UBC
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
YMENDLSEGVNPSVGRSTIGTSFGNVHLDRSKNEKVSRKSTSQTGNKSSK
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Horse: 85%; Human: 100%; Pig: 92%; Rabbit: 86%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
32kDa
Protein Length
294
NCBI Gene Symbol
PARPBP
Host or Source
Rabbit
Protein Name
PCNA-interacting partner
Gene Name URL
PARPBP
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