C11ORF80 Antibody - C-terminal region (ARP68096_P050)
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Product Specifications
CAS Number
9007-83-4
Gene Name
Chromosome 11 open reading frame 80
Gene Aliases
HYDM4, TOP6BL, TOPOVIBL
Gene ID
79703
Swiss Prot
Q8N6T0-2
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human C11ORF80
Target
Isoform 3: Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with SPO11, mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles.
Partner Proteins
UBC
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
KVFREITQHQFLHHCSCEVKQLTLEKKDSAQGTEDAPDNSSLELLADTSG
Applications
WB
Purification
Affinity purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Human: 100%; Rat: 83%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
53 kDa
Protein Length
485
NCBI Gene Symbol
C11ORF80
Host or Source
Rabbit
Protein Name
Type 2 DNA topoisomerase 6 subunit B-like
Gene Name URL
C11ORF80
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