TTI2 Antibody - N-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Aliases

MRT39, C8orf41

Gene ID

80185

Swiss Prot

Q6NXR4

Accession Number

NP_079391

Reactivity

Human, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human TTI2

Target

TTI2 is a regulator of the DNA damage response (DDR) . 'TTI2 is part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC) . 'TTI2, together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs.

Partner Proteins

FUS; UBC; SUMO1; NEDD8; EGFR; ELAVL1; RPAP3; PIH1D1; RUVBL2; TELO2; TTI1; RUVBL1; PRKDC; HSP90AA1; HSPA4

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

THSLEQPWTTPRSREVAREVLTSLLQVTECGSVAGFLHGENEDEKGRLSV

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 92%; Guinea Pig: 75%; Horse: 100%; Human: 100%; Pig: 92%; Rabbit: 75%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

56kDa

Protein Length

508

NCBI Gene Symbol

TTI2

Host or Source

Rabbit

Protein Name

TELO2-interacting protein 2

Gene Name URL

TTI2

Nucleotide Accession Number

NM_025115

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