CTU1 Antibody - C-terminal region
Product Specifications
CAS Number
9007-83-4
Gene Aliases
NCS6, ATPBD3
Gene ID
90353
Swiss Prot
Q7Z7A3
Accession Number
NP_660275
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human CTU1
Target
CTU1 plays a central role in 2-thiolation of mcm5S2U at tRNA wobble positions of tRNA (Lys), tRNA (Glu) and tRNA (Gln) . CTU1 directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
Partner Proteins
FAM96B; CIAO1; MMS19; CTU2; URM1; HSPA4
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
ALASRALCQACALLDGLNRGRPRLAIGKGRRGLDEEATPGTPGDPARPPA
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
38kDa
Protein Length
348
NCBI Gene Symbol
CTU1
Host or Source
Rabbit
Protein Name
Cytoplasmic tRNA 2-thiolation protein 1
Gene Name URL
CTU1
Nucleotide Accession Number
NM_145232
Curated Selection
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