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CTU1 Antibody - C-terminal region (ARP67471_P050)

Product Specifications

CAS Number

9007-83-4

Gene Aliases

NCS6, ATPBD3

Gene ID

90353

Swiss Prot

Q7Z7A3

Accession Number

NP_660275

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human CTU1

Target

CTU1 plays a central role in 2-thiolation of mcm5S2U at tRNA wobble positions of tRNA (Lys), tRNA (Glu) and tRNA (Gln) . CTU1 directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

Partner Proteins

FAM96B; CIAO1; MMS19; CTU2; URM1; HSPA4

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

ALASRALCQACALLDGLNRGRPRLAIGKGRRGLDEEATPGTPGDPARPPA

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

38kDa

Protein Length

348

NCBI Gene Symbol

CTU1

Host or Source

Rabbit

Protein Name

Cytoplasmic tRNA 2-thiolation protein 1

Gene Name URL

CTU1

Nucleotide Accession Number

NM_145232

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