MYSM1 Antibody - N-terminal region
Product Specifications
CAS Number
9007-83-4
Gene Aliases
2ADUB, BMFS4, 2A-DUB
Gene ID
114803
Swiss Prot
Q5VVJ2
Accession Number
NP_001078956
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human MYSM1
Target
MYSM1 is a metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. It preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. MYSM1 acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR) -induced gene activation.
Partner Proteins
UBC; DICER1; SUMO2; TUBB1; WDR77; STK38; PRMT5; KAT2B; HIST2H2AC; RBM10; KIF11; HSPA1A; HNRNPH1; EEF1A1
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
KLIGSRTVLQVKSYARQYFKNKVKCGLDKETPNQKTGHNLQVKNEDKGTK
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
91kDa
Protein Length
828
NCBI Gene Symbol
MYSM1
Host or Source
Rabbit
Protein Name
Histone H2A deubiquitinase MYSM1
Gene Name URL
MYSM1
Nucleotide Accession Number
NM_001085487
Curated Selection
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