EIF2B3 Antibody - middle region (ARP66344_P050)

Product Specifications

CAS Number

9007-83-4

Gene Aliases

EIF-2B, EIF2Bgamma

Gene ID

8891

Swiss Prot

Q9NR50

Accession Number

NP_065098

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of Human EIF2B3

Target

The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

UBC; C14orf166; RTCB; DIMT1; NELFB; EDC4; IGF2BP3; G3BP1; EIF2B2; EIF3C; YBX3; RFC4; QARS; NMT1; HNRNPM; MRE11A; ILF2; HNRNPU; FLII; FKBP3; DHX9; DDX1; ABCF1; FBXO6; EGFR; EIF2B5; EIF2B4; NDUFB8; EIF2B3; GOLM1; EIF2S2; EIF2S1; STC2; EIF2B1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

ENGSITSIRSELIPYLVRKQFSSASSQQGQEEKEEDLKKKELKSLDIYSF

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 93%; Yeast: 90%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

50kDa

Protein Length

452

NCBI Gene Symbol

EIF2B3

Host or Source

Rabbit

Protein Name

Translation initiation factor eIF-2B subunit gamma

Gene Name URL

EIF2B3

Nucleotide Accession Number

NM_020365

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