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FYCO1 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Aliases

CATC2, RUFY3, ZFYVE7, CTRCT18

Gene ID

79443

Swiss Prot

Q9BQS8

Accession Number

NP_078789

Reactivity

Human, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human FYCO1

Target

This gene encodes a protein that contains a RUN domain, FYVE-type zinc finger domain and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P) and the autophagosome marker LC3. Mutations in this gene are a cause of autosomal recessive congenital cataract-2 (CATC2) .

Partner Proteins

RAF1; UBC; PRMT6; KDM1A; MAP1LC3A; IQCB1; APP; MAP1LC3B; SEC24B; KIF23; TMPO; RPA3; RPA2; RPA1; MAP4; LMNA; KIF5B; EMD; FOXK1; CCAR1; CCZ1; C18orf8; MON1B; SEC23B

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

PLAQELEATRDSLDKKNQHLASFPGWLAMAQQKADTASDTKGRQEPIPSD

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Horse: 86%; Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

167kDa

Protein Length

1478

NCBI Gene Symbol

FYCO1

Host or Source

Rabbit

Protein Name

FYVE and coiled-coil domain-containing protein 1

Gene Name URL

FYCO1

Nucleotide Accession Number

NM_024513

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