FYCO1 Antibody - N-terminal region (ARP66172_P050)
Product Specifications
CAS Number
9007-83-4
Gene Aliases
CATC2, RUFY3, ZFYVE7, CTRCT18
Gene ID
79443
Swiss Prot
Q9BQS8
Accession Number
NP_078789
Reactivity
Human, Horse
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human FYCO1
Target
This gene encodes a protein that contains a RUN domain, FYVE-type zinc finger domain and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P) and the autophagosome marker LC3. Mutations in this gene are a cause of autosomal recessive congenital cataract-2 (CATC2) .
Partner Proteins
RAF1; UBC; PRMT6; KDM1A; MAP1LC3A; IQCB1; APP; MAP1LC3B; SEC24B; KIF23; TMPO; RPA3; RPA2; RPA1; MAP4; LMNA; KIF5B; EMD; FOXK1; CCAR1; CCZ1; C18orf8; MON1B; SEC23B
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
PLAQELEATRDSLDKKNQHLASFPGWLAMAQQKADTASDTKGRQEPIPSD
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Horse: 86%; Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
167kDa
Protein Length
1478
NCBI Gene Symbol
FYCO1
Host or Source
Rabbit
Protein Name
FYVE and coiled-coil domain-containing protein 1
Gene Name URL
FYCO1
Nucleotide Accession Number
NM_024513
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