MRPL12 Antibody - middle region
Product Specifications
CAS Number
9007-83-4
Gene Aliases
5c5-2, L12mt, MRPL7, RPML12, MRPL7/L12, MRP-L31/34
Gene ID
6182
Swiss Prot
P52815
Accession Number
NP_002940
Reactivity
Human, Dog
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human MRPL12
Target
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which forms homodimers. In prokaryotic ribosomes, two L7/L12 dimers and one L10 protein form the L8 protein complex.
Partner Proteins
MDM2; PARK2; TARDBP; MRPS27; ICT1; mug82; ADRB2; NPM1; SOX2; OLIG1; POLR1D; UBC; RARG; COX6A2; C1QBP; RPL18; RPL12; RPL11; RPL7A; RBM3; ILF3; HNRNPD; AK2; ACOX1; TMEM9; MRPL10; MRPL52; GADD45GIP1; EPPK1; MRPL1; MRPL9; MRPL11; MRPL41; MRPS9; MRPS26; NIT2
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
KKTLKIQDVGLVPMGGVMSGAVPAAAAQEAVEEDIPIAKERTHFTVRLTE
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Dog: 77%; Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
21kDa
Protein Length
198
NCBI Gene Symbol
MRPL12
Host or Source
Rabbit
Protein Name
39S ribosomal protein L12, mitochondrial
Gene Name URL
MRPL12
Nucleotide Accession Number
NM_002949
Curated Selection
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