IPO8 Antibody - C-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

Importin 8

Gene Aliases

RANBP8

Gene ID

10526

Swiss Prot

O15397

Accession Number

NP_001177924

Reactivity

Human, Rat, Dog, Guinea Pig, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human IPO8

Target

The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

UBC; EGFR; YWHAE; CBX5; ATXN1; CUL3; Trim28; AGO4; AGO3; AGO2; AGO1; KPNB1; RANGAP1; SRP19; RPL23A

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

PPAVDAVVGQIVPSILFLFLGLKQVCATRQLVNREDRSKAEKADMEENEE

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

96kDa

Protein Length

832

NCBI Gene Symbol

IPO8

Host or Source

Rabbit

Protein Name

Importin-8

Gene Name URL

IPO8

Nucleotide Accession Number

NM_001190995

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