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CTDP1 Antibody - C-terminal region (ARP65744_P050)

Product Specifications

Gene Name

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1

Gene Aliases

FCP1, CCFDN

Gene ID

9150

Swiss Prot

Q9Y5B0

Accession Number

NP_430255

Reactivity

Human, Mouse, Rat, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human CTDP1

Target

This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF, and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II), making it available for initiation of gene expression. Mutations in this gene are associated with congenital cataracts, facial dysmorphism and neuropathy syndrome (CCFDN) . Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Partner Proteins

UBC; CDK9; UPP1; PPP2CA; PPP1CA; POLR2A; POLR2C; GRK5; ELP2; ELP3; SUMO2; PRKDC; CDK8; CDK7; INTS8; MED15; MED4; INTS6; INTS1; INTS7; MED16; MED6; MED24; MED7; MED26; MED17; MED23; MED14; MED1; MED8; MED25; INTS3; POLR2J; ERH; POLR2B; STK38; PRMT5; HIST1H

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

AHAPDKEPELGGQEEGERDGLCGLGNGCADRKEAETESQNSELSGVTAGE

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

93kDa

Protein Length

867

NCBI Gene Symbol

CTDP1

Host or Source

Rabbit

Protein Name

RNA polymerase II subunit A C-terminal domain phosphatase

Gene Name URL

CTDP1

CAS Number

9007-83-4

Nucleotide Accession Number

NM_048368

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