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ARPC1B Antibody - C-terminal region

Product Specifications

Gene Name

Actin related protein 2/3 complex subunit 1B

Gene Aliases

ARC41, IMD71, PLTEID, p40-ARC, p41-ARC

Gene ID

10095

Swiss Prot

O15143

Accession Number

NP_005711

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human ARPC1B

Target

This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase.

Partner Proteins

SUMO2; UBC; SUMO1; NEDD8; BTF3L4; C14orf142; IPO11; TPRKB; PDCD4; ANP32B; ARPC2; ACTR2; ACTR3; ARPC3; ARPC4; ARPC5; TOM1L1; ANP32A; VBP1; UBE3A; TPD52L2; TPD52; RPA2; RANGAP1; PRKACB; PPP2R5D; METTL1; HSF1; DR1; DHPS; CALU; CALR; AARS; SRPK2; PAN2; WASL

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

RERFQNLDKKASSEGGTAAGAGLDSLHKNSVSQISVLSGGKAKCSQFCTT

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 79%; Guinea Pig: 100%; Human: 100%; Mouse: 86%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

41kDa

Protein Length

372

NCBI Gene Symbol

ARPC1B

Host or Source

Rabbit

Protein Name

Actin-related protein 2/3 complex subunit 1B

Gene Name URL

ARPC1B

CAS Number

9007-83-4

Nucleotide Accession Number

NM_005720

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