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FAM175A Antibody - C-terminal region (ARP65320_P050)

Selected Variant

ARP65320_P050

Size: 100 µL

Product Specifications

CAS Number

9007-83-4

Gene Name

Abraxas 1, BRCA1 A complex subunit

Gene Aliases

ABRA1, CCDC98, FAM175A

Gene ID

84142

Swiss Prot

Q6UWZ7

Accession Number

NP_620775

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human FAM175A

Target

This gene encodes a protein that binds to the C-terminal repeats of breast cancer 1 (BRCA1) through a phospho-SXXF motif. The encoded protein recruits ubiquitin interaction motif containing 1 protein to BRCA1 protein and is required for DNA damage resistance, DNA repair, and cell cycle checkpoint control. Pseudogenes of this gene are found on chromosomes 3 and 8. Alternative splicing results in multiple transcript variants.

Partner Proteins

FANCG; UIMC1; BRCA1; BRCC3; BABAM1; UBC; SUMO2; PAXIP1; MDC1; BARD1; BRE; HSPA4

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

TPQIIKHKALDLDDRWQFKRSRLLDTQDKRSKADTGSSNQDKASKMSSPE

Applications

WB

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

47 kDa

Protein Length

409

NCBI Gene Symbol

ABRAXAS1

Host or Source

Rabbit

Protein Name

BRCA1-A complex subunit Abraxas 1

Gene Name URL

ABRAXAS1

Nucleotide Accession Number

NM_139076.2

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