FAM175A Antibody - C-terminal region (ARP65320_P050)
Product Specifications
CAS Number
9007-83-4
Gene Name
Abraxas 1, BRCA1 A complex subunit
Gene Aliases
ABRA1, CCDC98, FAM175A
Gene ID
84142
Swiss Prot
Q6UWZ7
Accession Number
NP_620775
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human FAM175A
Target
This gene encodes a protein that binds to the C-terminal repeats of breast cancer 1 (BRCA1) through a phospho-SXXF motif. The encoded protein recruits ubiquitin interaction motif containing 1 protein to BRCA1 protein and is required for DNA damage resistance, DNA repair, and cell cycle checkpoint control. Pseudogenes of this gene are found on chromosomes 3 and 8. Alternative splicing results in multiple transcript variants.
Partner Proteins
FANCG; UIMC1; BRCA1; BRCC3; BABAM1; UBC; SUMO2; PAXIP1; MDC1; BARD1; BRE; HSPA4
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
TPQIIKHKALDLDDRWQFKRSRLLDTQDKRSKADTGSSNQDKASKMSSPE
Applications
WB
Purification
Affinity purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
47 kDa
Protein Length
409
NCBI Gene Symbol
ABRAXAS1
Host or Source
Rabbit
Protein Name
BRCA1-A complex subunit Abraxas 1
Gene Name URL
ABRAXAS1
Nucleotide Accession Number
NM_139076.2
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