NELFB Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Negative elongation factor complex member B

Gene Aliases

COBRA1, NELF-B

Gene ID

25920

Swiss Prot

Q8WX92

Accession Number

NP_056271

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human COBRA1

Target

NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2; MIM 606026), either NELFC or NELFD (TH1L; MIM 605297), and NELFE (RDBP; MIM 154040) . NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1; MIM 603555) and SPT5 (SUPT5H; MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]) .[supplied by OMIM, Mar 2008]

Partner Proteins

UBC; ABCF1; DIMT1; EDC4; IGF2BP3; SYNCRIP; EIF2B2; EIF2B3; EIF3C; YBX3; RPL23A; RFC4; PTBP1; PA2G4; YBX1; NMT1; MRE11A; ILF2; HNRNPU; FKBP3; DHX9; DDX1; KHDRBS3; DENR; YWHAB; MGST1; HSPA9; Dlg4; POLR2C; NELFB; SUPT5H; POLR2A; ATP1A1; ALDH3A2; NELFCD; CCT8

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

NCTEPLKAIEQFQTENGVLLPSLQSALPFLDLHGTPRLEFHQSVFDELRD

Applications

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol