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BLOC1S3 antibody - N-terminal region (ARP65298_P050)

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Product Specifications

Gene Name

Biogenesis of lysosomal organelles complex-1, subunit 3

Gene Aliases

RP, HPS8, BLOS3

Gene ID

388552

Swiss Prot

Q6QNY0

Accession Number

NP_997715

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Sheep, Zebrafish

Target

This gene encodes a protein that is a component of the BLOC1 multi-subunit protein complex. This complex is necessary for the biogenesis of specialized organelles of the endosomal-lysosomal system, including platelet dense granules and melanosomes. Mutations in this gene cause Hermansky-Pudlak syndrome 8, a disease characterized by lysosomal storage defects, bleeding due to platelet storage pool deficiency, and oculocutaneous albinism.

Partner Proteins

BLOC1S3; BLOC1S2; BLOC1S1; DTNBP1; BLOC1S5; BLOC1S6; SNAPIN

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

RGRPTGLRVAGEAAETDSEPEPEPEPTAAPRDLPPLVVQRESAEEAWGTE

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 86%; Goat: 79%; Guinea Pig: 86%; Horse: 79%; Human: 100%; Mouse: 100%; Rat: 100%; Sheep: 79%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

21kDa

Protein Length

202

NCBI Gene Symbol

BLOC1S3

Host or Source

Rabbit

Protein Name

Biogenesis of lysosome-related organelles complex 1 subunit 3

Gene Name URL

BLOC1S3

CAS Number

9007-83-4

Nucleotide Accession Number

NM_212550

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