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SRGAP2 Antibody - N-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

SLIT-ROBO Rho GTPase activating protein 2

Gene Aliases

FNBP2, SRGAP3, SRGAP2A, ARHGAP34

Gene ID

23380

Swiss Prot

P0DJJ0

Accession Number

NP_001258799

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SRGAP2

Target

This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus.

Partner Proteins

UBC; PPP2R1A; YWHAB; YWHAE; UBD; FASLG; HERC2; EXOC1; DISC1; YWHAG; MYO1G; YLPM1; ATAD3A; ITSN2; SLC25A12; WIPF1; WAS; DIAPH1; ROBO1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

AERFLAKTCSTKDQQFKKDQNVLSPVNCWNLLLNQVKRESRDHTTLSDIY

Applications

WB

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 87%; Dog: 100%; Guinea Pig: 87%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 87%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

53 kDa

Protein Length

459

NCBI Gene Symbol

SRGAP2

Host or Source

Rabbit

Protein Name

SLIT-ROBO Rho GTPase-activating protein 2

Gene Name URL

SRGAP2

Nucleotide Accession Number

NM_001170637.3

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