FKBP1A Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

FK506 binding protein 1A, 12kDa

Gene Aliases

FKBP1, PKC12, PKCI2, FKBP12, PPIASE, FKBP-12, FKBP-1A

Gene ID

2280

Swiss Prot

P62942

Accession Number

NP_000792

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Target

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.

Partner Proteins

AHSP; SF3B4; MID1; MTOR; TGFB1; UBC; BAG3; ACVRL1; BARD1; ZPR1; APP; ELAVL1; ACVR1B; SMAD7; TRPC3; FKBP4; TGFB1I1; GLMN; PPP3R1; YY1; TGFBR1; FKBP1A; RYR3; RYR1; ITPR1; DHFR; PPP3CA; BMPR1A; RPTOR

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

VQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLG

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 90%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 83%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

12 kDa

Protein Length

108

NCBI Gene Symbol

FKBP1A

Host or Source

Rabbit

Protein Name

Peptidyl-prolyl cis-trans isomerase FKBP1A

Gene Name URL

FKBP1A

Nucleotide Accession Number

NM_000801

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