KRT4 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Keratin 4

Gene Aliases

K4, CK4, CK-4, CYK4, WSN1

Gene ID

3851

Swiss Prot

F8VS64

Accession Number

NP_002263

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Sheep

Target

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Partner Proteins

KRT40; KRT38; KRT33B; KRT15; KRT13; WWOX; UBASH3B; SHC1; PIK3R2; GRB2; EPS15; CRK; CUL3; UBC; ATG4B; USP25; USPL1; USP1; UCHL1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

SGKGGPGFPVCPAGGIQEVTINQSLLTPLHVEIDPEIQKVRTEEREQIKL

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Pig: 93%; Rabbit: 100%; Rat: 100%; Sheep: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

56kDa

Protein Length

520

NCBI Gene Symbol

KRT4

Host or Source

Rabbit

Protein Name

Keratin, type II cytoskeletal 4

Gene Name URL

KRT4

Nucleotide Accession Number

NM_002272

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