ITGAV Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Aliases

CD51, MSK8, VNRA, VTNR

Gene ID

3685

Swiss Prot

E7EWZ6

Accession Number

NP_001138471

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human ITGAV

Target

ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8; 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR) . In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants.

Partner Proteins

UBC; EPHA2; THBS1; FN1; KRT3; MCAT; FBXO6; BCAR1; PXN; PHKA2; CSF1R; CBL; MMP2; ILK; PLP1; CALR; ANGPTL3; EDIL3; CYR61; PAK4; ITGB8; ADAM9; AUP1; CD47; PTK2; MMP14; P2RY2; L1CAM; AZGP1; TGFB1; THY1; F2R; PDGFRA; ITGB3; SPP1; ITGB5; ITGB6; ITGB1; NID1; ICA

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

PVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENG

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol