AQR Antibody - C-terminal region (ARP64428_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Aquarius homolog (mouse)

Gene Aliases

IBP160, fSAP164

Gene ID

9716

Swiss Prot

O60306

Accession Number

NP_055506

Reactivity

Human, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human AQR

Target

AQR is an intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. AQR plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. AQR may act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.

Partner Proteins

UBC; LGR4; SUZ12; RNF2; BMI1; ZNF830; WDR83; WDR77; RBM22; PQBP1; RBM4; EIF4A3; MAGOH; SIRT7; HNRNPA1; Prpf8; Cdc5l; Snw1; USP28

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

DTTPSETGATSTPEAIPALSETTPTVVGAVSAPAEANTPQDATSAPEETK

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol