PSTPIP1 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Proline-serine-threonine phosphatase interacting protein 1

Gene Aliases

H-PIP, PAPAS, CD2BP1, PSTPIP, CD2BP1L, CD2BP1S

Gene ID

9051

Swiss Prot

O43586

Accession Number

NP_003969

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

Target

The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome.

Partner Proteins

RTP5; TRAF3IP3; FBXL18; SH2D4A; PCDHB14; UBE2W; FAM90A1; PRPF31; LSM4; BUB3; ZNF175; TULP3; SPG7; SDCBP; MVP; WASL; DNM2; MED28; SHBG; KHDRBS1; WAS; TUBB; WIPF1; HSPA1A; CARS; ACTB; PTPN18; WASF2; WASF1; CD2AP; PTPN12; MEFV; ABL1; CD2; FASLG; BZW2; RPL36

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

HIQLALTLREELRSLEEFRERQKEQRKKYEAVMDRVQKSKLSLYKKAMES

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol