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PSTPIP1 antibody - N-terminal region (ARP64283_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Proline-serine-threonine phosphatase interacting protein 1

Gene Aliases

H-PIP, PAPAS, CD2BP1, PSTPIP, CD2BP1L, CD2BP1S

Gene ID

9051

Swiss Prot

O43586

Accession Number

NP_003969

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

Target

The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome.

Partner Proteins

RTP5; TRAF3IP3; FBXL18; SH2D4A; PCDHB14; UBE2W; FAM90A1; PRPF31; LSM4; BUB3; ZNF175; TULP3; SPG7; SDCBP; MVP; WASL; DNM2; MED28; SHBG; KHDRBS1; WAS; TUBB; WIPF1; HSPA1A; CARS; ACTB; PTPN18; WASF2; WASF1; CD2AP; PTPN12; MEFV; ABL1; CD2; FASLG; BZW2; RPL36

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

HIQLALTLREELRSLEEFRERQKEQRKKYEAVMDRVQKSKLSLYKKAMES

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 79%; Rat: 100%; Zebrafish: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

47kDa

Protein Length

416

NCBI Gene Symbol

PSTPIP1

Host or Source

Rabbit

Protein Name

Proline-serine-threonine phosphatase-interacting protein 1

Gene Name URL

PSTPIP1

Nucleotide Accession Number

NM_003978

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