CDK2AP1 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Cyclin-dependent kinase 2 associated protein 1

Gene Aliases

DOC1, ST19, DORC1, doc-1, p12DOC-1

Gene ID

8099

Swiss Prot

O14519

Accession Number

NP_004633

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human CDK2AP1

Target

The protein encoded by this gene is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. A similar gene in hamster was isolated from, and functions as a growth suppressor of normal keratinocytes.

Partner Proteins

MRFAP1L1; CCDC136; HDAC2; HDAC1; ZNF420; MTA3; VCP; CDK2AP2; Cebpb; HHV8GK18_gp81; ELAVL1; MBD3; MBD2; RBBP7; RBBP4; SRRM2; POLA1; CDK2; IGHA2; IGHA1; AMY1A

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

LLAIIEELGKEIRPTYAGSKSAMERLKRGIIHARGLVRECLAETERNARS

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

12kDa

Protein Length

115

NCBI Gene Symbol

CDK2AP1

Host or Source

Rabbit

Protein Name

Cyclin-dependent kinase 2-associated protein 1

Gene Name URL

CDK2AP1

Nucleotide Accession Number

NM_004642

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