UNC13D Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Unc-13 homolog D (C. elegans)

Gene Aliases

FHL3, HLH3, HPLH3, Munc13-4

Gene ID

201294

Swiss Prot

Q70J99

Accession Number

NP_954712

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human UNC13D

Target

This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.

Partner Proteins

UBC; CUL5; VPS37B; XRN2; LMNA; RAB27B; RAB27A

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

SGSEEPGEVPQTRLPLTYPAPNGDPILQLLEGRKGDREAQVFVRLRRHRA

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 93%; Guinea Pig: 92%; Horse: 93%; Human: 100%; Mouse: 92%; Rabbit: 86%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

119kDa

Protein Length

1090

NCBI Gene Symbol

UNC13D

Host or Source

Rabbit

Protein Name

Protein unc-13 homolog D

Gene Name URL

UNC13D

Nucleotide Accession Number

NM_199242

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MBS7007286-01 0.02 mg

Recombinant Dog Alpha-1B adrenergic receptor (ADRA1B)

Ask

View Details

MBS7007286-02 0.1 mg

Recombinant Dog Alpha-1B adrenergic receptor (ADRA1B)

Ask

View Details

MBS7007286-03 5x 0.1 mg

Recombinant Dog Alpha-1B adrenergic receptor (ADRA1B)

Ask

View Details

LH06116V 100 µg

KIR2DL4 (NM_002255) Human Over-expression Lysate

Ask

View Details

abx532668 96 Tests

Mouse Mediator of RNA polymerase II transcription subunit 6 (MED6) ELISA Kit

Ask

View Details

PPL00507 1 Each

PDONR223-PRMT1

Ask

View Details