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NOS1AP Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Nitric oxide synthase 1 (neuronal) adaptor protein

Gene Aliases

CAPON, NPHS22, 6330408P19Rik

Gene ID

9722

Swiss Prot

O75052

Accession Number

BAA32309

Reactivity

Human, Mouse, Rat, Cow, Guinea Pig, Horse, Yeast, Zebrafish

Target

This gene encodes a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS) . This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins. Alternative splicing results in multiple transcript variants encoding different isoforms.

Partner Proteins

FAM133A; TRAF4; APP; RASD1; SYN3; SYN2; LRP2; SYN1; NOS1; LRP1; LRP8

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

PEDTPPPAQGEALLGGLELIKFRESGIASEYESNTDESEERDSWSQEELP

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Yeast: 75%; Zebrafish: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

63kDa

Protein Length

586

NCBI Gene Symbol

NOS1AP

Host or Source

Rabbit

Protein Name

Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

Gene Name URL

NOS1AP

Nucleotide Accession Number

NM_001126060

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