RAP2A Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

RAP2A, member of RAS oncogene family

Gene Aliases

KREV, RAP2, K-REV, RbBP-30

Gene ID

5911

Swiss Prot

P10114

Accession Number

NP_066361

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Target

RAP2A is a small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading.

Partner Proteins

UBC; RPTOR; ELAVL1; RRP9; TM7SF2; PLG; SERPINA1; FTL; FKBP2; ENSA; EEF1A1; NEDD4; TNIK; RUNDC3A; GRIN1; RASIP1; RAPGEF5; RAPGEF6; ARHGAP29; RASSF5; MAP4K4; BMPR1B; GRIN2D; RGS14; RALGDS; SMAD1; TGFBR1; RAP2A; RAF1; MLLT4; FNTB; ACVR1; RAPGEF4; RAPGEF3; RA

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

QIIRVKRYEKVPVILVGNKVDLESEREVSSSEGRALAEEWGCPFMETSAK

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol