RAP2A antibody - C-terminal region (ARP64032_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

RAP2A, member of RAS oncogene family

Gene Aliases

KREV, RAP2, K-REV, RbBP-30

Gene ID

5911

Swiss Prot

P10114

Accession Number

NP_066361

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Target

RAP2A is a small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading.

Partner Proteins

UBC; RPTOR; ELAVL1; RRP9; TM7SF2; PLG; SERPINA1; FTL; FKBP2; ENSA; EEF1A1; NEDD4; TNIK; RUNDC3A; GRIN1; RASIP1; RAPGEF5; RAPGEF6; ARHGAP29; RASSF5; MAP4K4; BMPR1B; GRIN2D; RGS14; RALGDS; SMAD1; TGFBR1; RAP2A; RAF1; MLLT4; FNTB; ACVR1; RAPGEF4; RAPGEF3; RA

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

QIIRVKRYEKVPVILVGNKVDLESEREVSSSEGRALAEEWGCPFMETSAK

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 86%; Rat: 93%; Sheep: 93%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

20kDa

Protein Length

183

NCBI Gene Symbol

RAP2A

Host or Source

Rabbit

Protein Name

Ras-related protein Rap-2a

Gene Name URL

RAP2A

Nucleotide Accession Number

NM_021033

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