ICOSLG Antibody - N-terminal region
Product Specifications
CAS Number
9007-83-4
Gene Aliases
B7h, B7H2, GL50, B7-H2, B7RP1, CD275, ICOSL, LICOS, B7RP-1, ICOS-L
Gene ID
23308
Swiss Prot
O75144
Accession Number
NP_056074
Reactivity
Human, Cow, Guinea Pig, Horse, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human ICOSLG
Target
ICOSLG is a ligand for the T-cell-specific cell surface receptor ICOS. ICOSLG acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. ICOSLG could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.
Partner Proteins
ICOS
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
VDSRYRNRALMSPAGMLRGDFSLRLFNVTPQDEQKFHCLVLSQSLGFQEV
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Cow: 92%; Guinea Pig: 77%; Horse: 85%; Human: 100%; Pig: 92%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
33kDa
Protein Length
302
NCBI Gene Symbol
ICOSLG
Host or Source
Rabbit
Protein Name
ICOS ligand
Gene Name URL
ICOSLG
Nucleotide Accession Number
NM_015259
Curated Selection
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