What is the catalog number for PICALM Antibody - middle region?

The catalog number for PICALM Antibody - middle region is ARP63957_P050-25UL.

What sizes are available for PICALM Antibody - middle region?

PICALM Antibody - middle region is available in the following size(s): 25 µL.

Is PICALM Antibody - middle region in stock?

PICALM Antibody - middle region is currently made to order / not held in immediate stock. Contact us for lead time.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

PICALM Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Phosphatidylinositol binding clathrin assembly protein

Gene Aliases

LAP, CALM, CLTH

Gene ID

8301

Swiss Prot

Q13492

Accession Number

NP_009097

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Target

This gene encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. A chromosomal translocation t (10;11) (p13; q14) leading to the fusion of this gene and the MLLT10 gene is found in acute lymphoblastic leukemia, acute myeloid leukemia and malignant lymphomas. The polymorphisms of this gene are associated with the risk of Alzheimer disease.

Partner Proteins

UBC; PELI2; VCAM1; ITGA4; FN1; SIRT1; ILF3; EGFR; EEF1A1; DNM2; CD55; ABCC2; ATP6V1E1; AP2A1; SH3GLB2; FLOT1; HNRNPDL; SEC24D; SEC24C; ATP6V1F; HIP1R; LAMTOR3; ITSN1; EHD2; CASP8; CLTCL1; CASP3; PLCG1; DDIT3; CLTC

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

ALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQA

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol