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DIAPH1 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Diaphanous homolog 1 (Drosophila)

Gene Aliases

DIA1, DRF1, DFNA1, LFHL1, SCBMS, hDIA1

Gene ID

1729

Swiss Prot

O60610

Accession Number

NP_005210

Reactivity

Human, Mouse, Rat, Cow, Dog, Pig, Rabbit

Target

This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Partner Proteins

UBC; IQGAP1; WWOX; SMEK2; PRPF40A; PTPN23; COPZ1; WBP4; TCERG1; GAS7; NEDD4; KLC1; KIF5B; COPB1; ARCN1; APBB1; KLC4; UBD; gag-pol; VCAM1; GRB2; FN1; CENPA; HSPA4L; MYO1E; DCAF7; SRGAP2; XPO6; CDC7; PAX6; BAIAP2; RAC1; PKD2; RHOA; RHOC

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

TGVMDSLLEALQSGAAFRRKRGPRQANRKAGCAVTSLLASELTKDDAMAA

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 85%; Dog: 100%; Human: 100%; Mouse: 93%; Pig: 92%; Rabbit: 86%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

141kDa

Protein Length

1272

NCBI Gene Symbol

DIAPH1

Host or Source

Rabbit

Protein Name

Protein diaphanous homolog 1

Gene Name URL

DIAPH1

Nucleotide Accession Number

NM_005219

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