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MCPH1 Antibody - C-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

Microcephalin 1

Gene Aliases

MCT, BRIT1

Gene ID

79648

Swiss Prot

E9PH63

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human MCPH1

Target

This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome.

Partner Proteins

KDM1A; PHF11; TADA2A; ABCC2; E2F1; CDC27; CHD4; H2AFX; CHEK1; MDC1; TP53BP1; SMARCC2; SMARCC1; SMARCB1; SMARCA4; SMARCA2; RAD51; NBN; MCM2; BRCA2; ATR; ATM; RPA1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

EAVGLKSTQNKGTTSKISNSSEGEAQSEHEPCFIVDCNMETSTEEKENLP

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

61kDa

Protein Length

562

NCBI Gene Symbol

MCPH1

Host or Source

Rabbit

Protein Name

Microcephalin Ensembl ENSP00000430768

Gene Name URL

MCPH1

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